Library
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Pituitary macroadenomas are large, non-cancerous tumors of the pituitary gland that are either functional (secrete hormones) or non-functional (do not secrete hormones). They are more common in dogs than cats. Clinical signs depend on the type of tumor. This handout outlines signs, diagnosis, and treatment.
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Clinical signs of pituitary tumors depend on whether the tumor is functional or non-functional. Functional tumors can cause Cushing's disease in dogs and can cause acromegaly and insulin-resistant diabetes in cats. Non-functional pituitary tumors can enlarge to cause neurological signs. Diagnosis is based on the history, bloodwork, urinalysis, and sometimes a CT scan or MRI. Medical therapy is often the treatment of choice for functional tumors. Radiation therapy is another option and is usually the primary treatment for non-functional tumors.
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Plasma cell tumors develop as a result of dysregulated production of plasma cells and are relatively uncommon in dogs and cats. Some plasma cell tumors are benign and the most common locations for these tumors are the head, feet, lips, mouth, and ears. The treatment of choice for benign plasma cell tumors is surgical removal, with little to no recurrence if completely excised. Conversely, multiple myeloma is a very malignant cancer that is usually treated with chemotherapy.
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Pleural effusion is the abnormal accumulation of fluid in the chest cavity. Fluid accumulates in the pleural sac, not the lungs, so the lungs are essentially floating in a chest full of fluid. This fluid occupies space within the chest, so the lungs cannot expand as fully as they should. Treatment and prognosis vary depending on the underlying cause.
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This handout explains post-vaccination sarcomas (also called injection-site sarcomas) in cats. They are a rare consequence of vaccine injections (and other drugs or materials) that can cause a very aggressive form of cancer at the site of the injection. The incidence of this condition, as well as precautions you and your veterinarian can take, are highlighted.
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Tumors of the prostate are relatively uncommon in dogs and extremely rare in cats. Clinical signs include bloody urine, or straining to urinate or defecate. Metastasis to the pelvic bone and/or lumbar spine is likely. Diagnosis and treatment options are discussed. Prognosis is considered poor.
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Radiation is a type of energy produced naturally by the sun, earth, and rocks and artificially by machines. Although several types of tumors can be treated with radiation therapy alone (e.g., nasal tumors, brain tumors, and certain types of lymphoma), radiation therapy is most commonly used to destroy or limit the growth of cancer cells left behind (i.e., microscopic disease) after a tumor has been surgically removed. Side effects depend on the type and location of the tumor and its surrounding tissues.
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Salivary gland tumors are rare in dogs and cats. The mandibular and parotid glands are most commonly affected. Signs include swelling of the upper neck or ear base, halitosis, anorexia, weight loss, difficulty eating, pain, and lethargy. The treatment of choice is usually surgical excision. If complete excision is not possible, adjunct radiation therapy may be pursued.
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A seizure, also known as a convulsion or fit, is a temporary, involuntary disturbance of normal brain function. If abnormal brain activity occurs in the motor cortex of the brain, it may cause uncontrollable muscle activity. Epilepsy is a condition that involves repeated seizures that may occur alone or in clusters. These seizures may be infrequent and unpredictable or they may occur at regular intervals.
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Soft tissue sarcomas are a broad category of tumors that can develop over the chest, back, side, legs, and facial tissues of your pet. The clinical signs depend on where the tumor is located and the tissues that are affected. Often, pets have a noticeable mass that is growing in size. One of the biggest concerns with soft tissue sarcomas is their ability to invade the local surrounding tissues. The most commonly pursued treatment is surgery. Chemotherapy is not usually pursued as a primary treatment unless surgery or radiation are not options for your pet based on the tumor size or location.
